Open AccessSerum Free Light Chains and the Risk of ESRD and Death in CKD
Author(s) -
Richard Haynes,
Colin A. Hutchison,
Jonathan Emberson,
Tanaji Dasgupta,
David C. Wheeler,
Jonathan N. Townend,
Martin Landray,
Paul Cockwell
Publication year - 2011
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.03350411
Subject(s) - medicine , intensive care medicine , cardiology
Associations between inflammation and ESRD and death in chronic kidney disease are well established. However, the potential role of the adaptive immune system is uncertain. We aimed to prospectively study the relevance of the adaptive immune system to ESRD and mortality by measuring monoclonal and polyclonal excesses of highly sensitive serum free light chains (sFLCs).
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