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Evolving Calciphylaxis—What Randomized, Controlled Trials Can Contribute to the Capture of Rare Diseases
Author(s) -
Markus Ketteler,
Patrick Biggar
Publication year - 2015
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.03350315
Subject(s) - calciphylaxis , medicine , cinacalcet , secondary hyperparathyroidism , population , surgery , hemodialysis , dialysis , randomized controlled trial , disease , parathyroid hormone , environmental health , calcium
Calciphylaxis or calcific uremic arteriolopathy is a rare but disastrous and life-threatening disease mostly affecting patients on dialysis. It is characterized by very painful, ulcerating, and, finally, necrotic skin lesions ([Figure 1][1]), which in histology, show calcifications in the media of

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