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Kidney Support in Children using an Ultrafiltration Device
Author(s) -
Shina Me,
J. J. Broderick,
Raj Munshi,
Lynn Dill,
Bradley DePaoli,
Sahar Fathallah-Shaykh,
Donna Claes,
Stuart L. Goldstein,
David J. Askenazi
Publication year - 2019
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.03240319
Subject(s) - medicine , volume overload , ultrafiltration (renal) , extracorporeal , hemofiltration , intravascular volume status , renal replacement therapy , intensive care medicine , heart failure , hemodialysis , surgery , blood pressure , chemistry , chromatography
Provision of kidney replacement therapy (KRT) to manage kidney injury and volume overload in critically ill neonates and small children is technically challenging. The use of machines designed for adult-sized patients, necessitates large catheters, a high extracorporeal volume relative to patient size, and need for blood priming. The Aquadex FlexFlow System (CHF Solutions Inc., Eden Prairie, MN) is an ultrafiltration device designed for fluid removal in adults with diuretic resistant heart failure. It has an extracorporeal volume of 33 ml, which can potentially mitigate some complications seen at onset of KRT in smaller infants.

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