Association of Urine α1-Microglobulin with Kidney Function Decline and Mortality in HIV-Infected Women
Author(s) -
Vasantha Jotwani,
Rebecca Scherzer,
Alison G. Abraham,
Michelle M. Estrella,
Michael Bennett,
Mardge H. Cohen,
M. Nowicki,
Anjali Sharma,
Mary Young,
Phyllis C. Tien,
Joachim H. Ix,
Mark J. Sarnak,
Chirag R. Parikh,
Michael G. Shlipak
Publication year - 2014
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.03220314
Subject(s) - medicine , beta 2 microglobulin , confidence interval , renal function , urine , creatinine , albuminuria , kidney disease , gastroenterology
Despite advances in therapy, HIV-infected individuals remain at higher risk for kidney dysfunction than uninfected individuals. It was hypothesized that urine levels of α1-microglobulin, a biomarker of proximal tubular dysfunction, would predict kidney function decline and mortality risk in HIV-infected and uninfected women.
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