Open AccessThe Role of Bicarbonate in CKD
Author(s) -
Eric E. Simon,
L. Lee Hamm
Publication year - 2013
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.03190313
Subject(s) - metabolic acidosis , medicine , acidosis , hyperkalemia , endocrinology , renal tubular acidosis , nephron , kidney disease , bicarbonate , intensive care medicine , kidney
The metabolic acidosis that commonly accompanies CKD may be the result of several processes. These include decreased nephron mass with decreased ammonia production, decreased proton secretion, and hyperkalemia which suppresses ammoniagenesis; ultimately, all of these involve the production and
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