Relationship between Epoetin Alfa Dose and Mortality | Zendy

Ouhong Wang | Zendy; Ryan D. Kilpatrick | Zendy; Cathy W. Critchlow | Zendy; Ling Xiang | Zendy; Brian D. Bradbury | Zendy; David T. Gilbertson | Zendy; Allan J. Collins | Zendy; Kenneth J. Rothman | Zendy; John Acquavella | Zendy

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Relationship between Epoetin Alfa Dose and Mortality

Author(s) -

Ouhong Wang,

Ryan D. Kilpatrick,

Cathy W. Critchlow,

Ling Xiang,

Brian D. Bradbury,

David T. Gilbertson,

Allan J. Collins,

Kenneth J. Rothman,

John Acquavella

Publication year - 2009

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.03040509

Subject(s) - medicine , marginal structural model , hazard ratio , confidence interval , epoetin alfa , confounding , proportional hazards model , observational study , dosing , truncation (statistics) , anemia , statistics , mathematics

Observational studies relating epoetin alfa (EPO) dose and mortality frequently use analytic methods that do not control time-dependent confounding by indication (CBI). The relationship between EPO dose and 1-year mortality, adjusting for the effects of time-dependent CBI, was examined using a marginal structural model.

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