Hyperfiltration Affects Accuracy of Creatinine eGFR Measurement
Author(s) -
ShihHan S. Huang,
Ajay P. Sharma,
Abeer Yasin,
Robert M. Lindsay,
William F. Clark,
Guido Filler
Publication year - 2010
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.02760310
Subject(s) - medicine , creatinine , renal function , urology , glomerular hyperfiltration , kidney , diabetic nephropathy
Surrogate markers such as creatinine, cystatin C (CysC), and beta trace protein (BTP) have been used to estimate GFR (eGFR). The accuracy of eGFR may be altered with hyperfiltration and differences in filtration fraction (FF). It is hypothesized that the accuracy of creatinine for eGFR may be affected by hyperfiltration and different effective renal plasma flow (ERPF).
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