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Effluent Volume in Continuous Renal Replacement Therapy Overestimates the Delivered Dose of Dialysis
Author(s) -
Rolando ClaureDel Granado,
Etienne Macedo,
Glenn M. Chertow,
Sharon Soroko,
Jonathan Himmelfarb,
T. Alp İkizler,
Yen–Hsuan Ni,
Ravindra L. Mehta
Publication year - 2010
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.02500310
Subject(s) - medicine , renal replacement therapy , dialysis , urology , volume (thermodynamics) , intensive care medicine , physics , quantum mechanics
Studies examining dose of continuous renal replacement therapy (CRRT) and outcomes have yielded conflicting results. Most studies considered the prescribed dose as the effluent rate represented by ml/kg per hour and reported this volume as a surrogate of solute removal. Because filter fouling can reduce the efficacy of solute clearance, the actual delivered dose may be substantially lower than the observed effluent rate.

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