Transplant Glomerulopathy May Occur in the Absence of Donor-Specific Antibody and C4d Staining | Zendy

Enver Akalin | Zendy; Rajani Dinavahi | Zendy; Steven Dikman | Zendy; Graciela de Boccardo | Zendy; Rex Friedlander | Zendy; Bernd Schröppel | Zendy; Vinita Sehgal | Zendy; Jonathan S. Bromberg | Zendy; Peter S. Heeger | Zendy; Barbara Murphy | Zendy

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Transplant Glomerulopathy May Occur in the Absence of Donor-Specific Antibody and C4d Staining

Author(s) -

Enver Akalin,

Rajani Dinavahi,

Steven Dikman,

Graciela de Boccardo,

Rex Friedlander,

Bernd Schröppel,

Vinita Sehgal,

Jonathan S. Bromberg,

Peter S. Heeger,

Barbara Murphy

Publication year - 2007

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.02420607

Subject(s) - medicine , staining , glomerulopathy , proteinuria , nephropathy , biopsy , antibody , gastroenterology , transplantation , creatinine , urology , kidney transplantation , pathology , kidney , immunology , endocrinology , diabetes mellitus

Transplant glomerulopathy (TGP) has been proposed to be a component of chronic antibody-mediated rejection (AMR). We have studied 36 patients with TGP and 51 patients with chronic allograft nephropathy (CAN) but without TGP for C4d staining and donor-specific anti-HLA antibodies (DSA) to investigate the alloantibody-mediated mechanisms.

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