Association of Hemoglobin Variability and Mortality among Contemporary Incident Hemodialysis Patients
Author(s) -
Steven M. Brunelli,
Katherine E. Lynch,
Elizabeth Ankers,
Marshall M. Joffe,
Wei Yang,
Ravi Thadhani,
Harold I. Feldman
Publication year - 2008
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.02390508
Subject(s) - medicine , hazard ratio , confidence interval , hemodialysis , hemoglobin , proportional hazards model , anemia , population , retrospective cohort study , cohort , demography , environmental health , sociology
Evidence exists that variability in hemoglobin may be an independent risk factor for mortality among hemodialysis patients. These observations were based on a 1996 cohort, a time when anemia management differed greatly from present. Design, settings, participants and measurements: A retrospective cohort study of patients incident to Fresenius Medical Care units between 2004 and 2005 (n = 6644). Hemoglobin variability (Hgb-Var) was defined for each subject as the residual SD of a linear regression model of time on hemoglobin.
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