Clinical Analysis of Perioperative Complement Activity during Ischemia/Reperfusion Injury following Renal Transplantation | Zendy

Wojciech Błogowski | Zendy; Barbara Dołęgowska | Zendy; Daria Sałata | Zendy; Marta Budkowska | Zendy; Leszek Domański | Zendy; Teresa Starzyńska | Zendy

Open Access

Clinical Analysis of Perioperative Complement Activity during Ischemia/Reperfusion Injury following Renal Transplantation

Author(s) -

Wojciech Błogowski,

Barbara Dołęgowska,

Daria Sałata,

Marta Budkowska,

Leszek Domański,

Teresa Starzyńska

Publication year - 2012

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.02200312

Subject(s) - medicine , transplantation , reperfusion injury , perioperative , ischemia , renal ischemia , cardiology , acute kidney injury , kidney transplantation , intensive care medicine , anesthesia

The complement cascade seems to be an important mediator modulating renal ischemia/reperfusion injury. This study analyzed whether significant changes occur in the levels of a terminal panel of complement molecules (C3a, C5a, and C5b-9/membrane attack complex) during the early phase of human kidney allograft reperfusion and evaluated the potential association of these changes with clinical post-transplant graft function in kidney transplant recipients.

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