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Cinacalcet Effectively Reduces Parathyroid Hormone Secretion and Gland Volume Regardless of Pretreatment Gland Size in Patients with Secondary Hyperparathyroidism
Author(s) -
Hirotaka Komaba,
Shohei Nakanishi,
Akira Fujimori,
Motoko Tanaka,
Jeongsoo Shin,
Koji Shibuya,
Masato Nishioka,
Hirohito Hasegawa,
Takeshi Kurosawa,
Masafumi Fukagawa
Publication year - 2010
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.02110310
Subject(s) - cinacalcet , medicine , parathyroid gland , parathyroid hormone , secondary hyperparathyroidism , endocrinology , urology , hyperparathyroidism , parathyroid chief cell , calcimimetic , hemodialysis , calcium
Cinacalcet is effective in reducing serum parathyroid hormone (PTH) in patients with secondary hyperparathyroidism. However, it has not been proven whether parathyroid gland size predicts response to therapy and whether cinacalcet is capable of inducing a reduction in parathyroid volume.

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