Long-Term Dose-Dependent Agalsidase Effects on Kidney Histology in Fabry Disease | Zendy

Rannveig Skrunes | Zendy; Camilla Tøndel | Zendy; Sabine Leh | Zendy; Kristin Kampevold Larsen | Zendy; Gunnar Houge | Zendy; Einar Skulstad Davidsen | Zendy; Carla E. M. Hollak | Zendy; André B. P. Kuilenburg | Zendy; Frédéric M. Vaz | Zendy; Einar Svarstad | Zendy

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Long-Term Dose-Dependent Agalsidase Effects on Kidney Histology in Fabry Disease

Author(s) -

Rannveig Skrunes,

Camilla Tøndel,

Sabine Leh,

Kristin Kampevold Larsen,

Gunnar Houge,

Einar Skulstad Davidsen,

Carla E. M. Hollak,

André B. P. Kuilenburg,

Frédéric M. Vaz,

Einar Svarstad

Publication year - 2017

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.01820217

Subject(s) - medicine , fabry disease , histology , kidney , term (time) , fabry's disease , urology , disease , physics , quantum mechanics

Dose-dependent clearing of podocyte globotriaosylceramide has previously been shown in patients with classic Fabry disease treated with enzyme replacement. Our study evaluates the dose-dependent effects of agalsidase therapy in serial kidney biopsies of patients treated for up to 14 years.

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