Effects of Rituximab on Morphofunctional Abnormalities of Membranous Glomerulopathy
Author(s) -
Piero Ruggenenti,
Paolo Cravedi,
Maria Chiara Sghirlanzoni,
Elena Gagliardini,
Sara Conti,
Flavio Gaspari,
Gianfranco Marchetti,
Mauro Abbate,
Giuseppe Remuzzi
Publication year - 2008
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.01730408
Subject(s) - medicine , renal function , interquartile range , rituximab , urology , gastroenterology , nephrotic syndrome , membranous nephropathy , benazepril , nephropathy , renal biopsy , pathology , endocrinology , kidney , glomerulonephritis , blood pressure , lymphoma , diabetes mellitus
In idiopathic membranous nephropathy (IMN), CD(20) B-cell depletion by rituximab may induce nephrotic syndrome (NS) remission. Whether this is associated with kidney function restoration and regression of the glomerular pathology was evaluated.
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