Effects of Lanthanum Carbonate on the Absorption and Oral Bioavailability of Ciprofloxacin | Zendy

Priscilla How | Zendy; James H. Fischer | Zendy; José A.L. Arruda | Zendy; Alan H. Lau | Zendy

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Effects of Lanthanum Carbonate on the Absorption and Oral Bioavailability of Ciprofloxacin

Author(s) -

Priscilla How,

James H. Fischer,

José A.L. Arruda,

Alan H. Lau

Publication year - 2007

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.01580407

Subject(s) - ciprofloxacin , pharmacokinetics , medicine , crossover study , bioavailability , oral administration , lanthanum carbonate , pharmacology , urine , sevelamer , chemistry , kidney disease , antibiotics , biochemistry , hyperphosphatemia , alternative medicine , pathology , placebo

Phosphate binders such as calcium salts or sevelamer, a cationic polymer, can markedly reduce absorption of oral ciprofloxacin. This randomized, open-label, two-way, crossover study examined the influence of the cation lanthanum on systemic ciprofloxacin exposure after oral administration.

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