Immunosuppression and Renal Outcome in Congenital and Pediatric Steroid-Resistant Nephrotic Syndrome | Zendy

Anja Büscher | Zendy; Birgitta Kranz | Zendy; Rainer Büscher | Zendy; Friedhelm Hildebrandt | Zendy; Bernd Dworniczak | Zendy; Petra Pennekamp | Zendy; Eberhard Kuwertz-Bröking | Zendy; AnneMargret Wingen | Zendy; Ulrike John | Zendy; Markus J. Kemper | Zendy; L.A.H. Monnens | Zendy; Peter F. Hoyer | Zendy; Stefanie Weber | Zendy; Martin Konrad | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Immunosuppression and Renal Outcome in Congenital and Pediatric Steroid-Resistant Nephrotic Syndrome

Author(s) -

Anja Büscher,

Birgitta Kranz,

Rainer Büscher,

Friedhelm Hildebrandt,

Bernd Dworniczak,

Petra Pennekamp,

Eberhard Kuwertz-Bröking,

AnneMargret Wingen,

Ulrike John,

Markus J. Kemper,

L.A.H. Monnens,

Peter F. Hoyer,

Stefanie Weber,

Martin Konrad

Publication year - 2010

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.01190210

Subject(s) - medicine , nephrotic syndrome , immunosuppression , renal function , population , genotyping , focal segmental glomerulosclerosis , congenital nephrotic syndrome , pediatrics , gastroenterology , glomerulonephritis , kidney , genotype , proteinuria , gene , genetics , biology , environmental health

Mutations in podocyte genes are associated with steroid-resistant nephrotic syndrome (SRNS), mostly affecting younger age groups. To date, it is unclear whether these patients benefit from intensified immunosuppression with cyclosporine A (CsA). The aim of this study was to evaluate the influence of podocyte gene defects in congenital nephrotic syndrome (CNS) and pediatric SRNS on the efficacy of CsA therapy and preservation of renal function.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research