Effect of Patiromer on Urinary Ion Excretion in Healthy Adults | Zendy

David A. Bushinsky | Zendy; David M. Spiegel | Zendy; Coleman Gross | Zendy; Wade W. Benton | Zendy; Jeanene Fogli | Zendy; Kathleen M. Hill Gallant | Zendy; Charles Du Mond | Zendy; Geoffrey A. Block | Zendy; Matthew R. Weir | Zendy; Bertram Pitt | Zendy

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Effect of Patiromer on Urinary Ion Excretion in Healthy Adults

Author(s) -

David A. Bushinsky,

David M. Spiegel,

Coleman Gross,

Wade W. Benton,

Jeanene Fogli,

Kathleen M. Hill Gallant,

Charles Du Mond,

Geoffrey A. Block,

Matthew R. Weir,

Bertram Pitt

Publication year - 2016

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.01170216

Subject(s) - urine , medicine , excretion , potassium , calcium , sodium , endocrinology , crossover study , magnesium , urinary system , urine sodium , regimen , urology , chemistry , pathology , placebo , alternative medicine , organic chemistry

Patiromer is a nonabsorbed potassium-binding polymer that uses calcium as the counterexchange ion. The calcium released with potassium binding has the potential to be absorbed or bind phosphate. Because binding is not specific for potassium, patiromer can bind other cations. Here, we evaluate the effect of patiromer on urine ion excretion in healthy adults, which reflects gastrointestinal ion absorption.

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