Interferon-γ Release Assays for Diagnosing Mycobacterium tuberculosis Infection in Renal Dialysis Patients | Zendy

Kevin Winthrop | Zendy; Melissa Nyendak | Zendy; Helene Calvet | Zendy; Peter Oh | Zendy; Melanie Lo | Zendy; Gwendolyn Swarbrick | Zendy; Carol Johnson | Zendy; David Lewinsohn | Zendy; Gerald H. Mazurek | Zendy

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Interferon-γ Release Assays for Diagnosing Mycobacterium tuberculosis Infection in Renal Dialysis Patients

Author(s) -

Kevin Winthrop,

Melissa Nyendak,

Helene Calvet,

Peter Oh,

Melanie Lo,

Gwendolyn Swarbrick,

Carol Johnson,

David Lewinsohn,

Gerald H. Mazurek

Publication year - 2008

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.01010208

Subject(s) - medicine , elispot , tuberculosis , tuberculin , mycobacterium tuberculosis , quantiferon , immunology , hemodialysis , prospective cohort study , latent tuberculosis , tuberculosis diagnosis , immune system , pathology , t cell

End-stage renal disease (ESRD) patients are at high risk for tuberculosis (TB). IFN-gamma release assays that assess immune responses to specific TB antigens offer potential advantages over tuberculin skin testing (TST) in screening such patients for Mycobacterium tuberculosis infection. This study sought to determine whether IFN-gamma release assay results are more closely associated with recent TB exposure than TST results.

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