The Origin of Multiple Molecular Forms in Urine of HNL/NGAL
Author(s) -
Linjun Cai,
Jenny Rubin,
Wenyu Han,
Per Venge,
Shengyuan Xu
Publication year - 2010
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.00980110
Subject(s) - lipocalin , urine , antibody , medicine , urinary system , blot , biomarker , epitope , acute kidney injury , kidney , immunology , microbiology and biotechnology , biology , gene , biochemistry
Several molecular forms of human neutrophil lipocalin/neutrophil gelatinase-associated lipocalin (HNL/NGAL), a novel biomarker for acute kidney injury (AKI), have been found in urine. The origin of these different forms and the effect of antibody configuration on assay performances were investigated in this report.
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