Dietary Sodium Restriction and Association with Urinary Marinobufagenin, Blood Pressure, and Aortic Stiffness | Zendy

Kristen Jablonski | Zendy; Olga V. Fedorova | Zendy; Matthew L. Racine | Zendy; Candace J. Geolfos | Zendy; Phillip E. Gates | Zendy; Michel Chonchol | Zendy; Bradley S. Fleenor | Zendy; Edward G. Lakatta | Zendy; Alexei Y. Bagrov | Zendy; Douglas R. Seals | Zendy

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Dietary Sodium Restriction and Association with Urinary Marinobufagenin, Blood Pressure, and Aortic Stiffness

Author(s) -

Kristen Jablonski,

Olga V. Fedorova,

Matthew L. Racine,

Candace J. Geolfos,

Phillip E. Gates,

Michel Chonchol,

Bradley S. Fleenor,

Edward G. Lakatta,

Alexei Y. Bagrov,

Douglas R. Seals

Publication year - 2013

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.00900113

Subject(s) - medicine , blood pressure , sodium , dietary sodium , urinary system , endocrinology , cardiology , urology , chemistry , organic chemistry

Systolic BP and large elastic artery stiffness both increase with age and are reduced by dietary sodium restriction. Production of the natriuretic hormone marinobufagenin, an endogenous α1 Na+,K+-ATPase inhibitor, is increased in salt-sensitive hypertension and contributes to the rise in systolic BP during sodium loading.

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