Immune Responses after a Third Dose of mRNA Vaccine Differ in Virus-Naive versus SARS-CoV-2– Recovered Dialysis Patients
Author(s) -
Philippe Attias,
Imane Azzaoui,
Khalil El Karoui,
A. SELLE,
Aurélien Sokal,
Pascal Chappert,
Philippe Grimbert,
I. Fernández,
Magali BouvierAlias,
Chloé Samson,
Djamal Dahmane,
Philippe Rieu,
Patrice Nizard,
Slim Fourati,
Hamza Sakhi,
Matthieu Mahévas
Publication year - 2022
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.00830122
Subject(s) - medicine , immune system , dialysis , covid-19 , virology , virus , sars virus , immunology , outbreak , disease , infectious disease (medical specialty)
After two doses of mRNA vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), patients on dialysis show a defective humoral response, but a third dose could increase anti-SARS-CoV-2 spike IgG titers. Responses could be different in virus-naive and SARS-CoV-2-recovered patients on dialysis. However, characterization of memory B cell response after three doses is lacking.
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