Comparison of Insulin Action on Glucose versus Potassium Uptake in Humans | Zendy

Trang Quynh Nguyen | Zendy; Naim M. Maalouf | Zendy; Khashayar Sakhaee | Zendy; Orson W. Moe | Zendy

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Comparison of Insulin Action on Glucose versus Potassium Uptake in Humans

Author(s) -

Trang Quynh Nguyen,

Naim M. Maalouf,

Khashayar Sakhaee,

Orson W. Moe

Publication year - 2011

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.00750111

Subject(s) - potassium , medicine , endocrinology , glucose uptake , insulin , glucose clamp technique , diabetes mellitus , type 2 diabetes , sodium , extracellular , intracellular , carbohydrate metabolism , insulin resistance , chemistry , pancreatic hormone , biochemistry , organic chemistry

Insulin has several physiologic actions that include stimulation of cellular glucose and potassium uptake. The ability of insulin to induce glucose uptake by cells is impaired in type 2 diabetes mellitus, but whether potassium uptake is similarly impaired is not known. This study examines whether the cellular uptake of these molecules is regulated in concert or independently.

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