Open AccessUrinary Biomarkers in the Clinical Prognosis and Early Detection of Acute Kidney Injury
Author(s) -
Jay L. Koyner,
Vishal S. Vaidya,
Michael Bennett,
Qing Ma,
Elaine M. Worcester,
Shahab A. Akhter,
Jai Raman,
Valluvan Jeevanandam,
Micheal F. O'Connor,
Prasad Devarajan,
Joseph V. Bonventre,
Patrick Murray
Publication year - 2010
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.00740110
Subject(s) - medicine , acute kidney injury , creatinine , lipocalin , cystatin c , urinary system , stage (stratigraphy) , receiver operating characteristic , urology , biomarker , intensive care unit , oliguria , gastroenterology , kidney disease , renal function , intensive care medicine , biochemistry , chemistry , biology , paleontology
Several novel urinary biomarkers have shown promise in the early detection and diagnostic evaluation of acute kidney injury (AKI). Clinicians have limited tools to determine which patients will progress to more severe forms of AKI at the time of serum creatinine increase. The diagnostic and prognostic utility of novel and traditional AKI biomarkers was evaluated during a prospective study of 123 adults undergoing cardiac surgery.