Serum Creatinine Levels Are Significantly Influenced by Renal Size in the Normal Pediatric Population | Zendy

Giacomo Di Zazzo | Zendy; Gilda Stringini | Zendy; Maria Chiara Matteucci | Zendy; Maurizio Muraca | Zendy; S. Malena | Zendy; Francesco Emma | Zendy

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Serum Creatinine Levels Are Significantly Influenced by Renal Size in the Normal Pediatric Population

Author(s) -

Giacomo Di Zazzo,

Gilda Stringini,

Maria Chiara Matteucci,

Maurizio Muraca,

S. Malena,

Francesco Emma

Publication year - 2010

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.00580110

Subject(s) - medicine , creatinine , renal function , population , urology , environmental health

Clinical and experimental data have shown that differences in nephron endowment result in differences in renal mass and predisposition to chronic renal failure, hypertension, and proteinuria. We hypothesized that a significant proportion of the variance in GFR, as estimated by serum creatinine, is attributable to differences in renal size in normal children.

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