Evidence of Extraordinary Growth in the Progressive Enlargement of Renal Cysts | Zendy

Jared J. Grantham | Zendy; Larry T. Cook | Zendy; Louis H. Wetzel | Zendy; Melissa A. Cadnapaphornchai | Zendy; Kyongtae T. Bae | Zendy

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Evidence of Extraordinary Growth in the Progressive Enlargement of Renal Cysts

Author(s) -

Jared J. Grantham,

Larry T. Cook,

Louis H. Wetzel,

Melissa A. Cadnapaphornchai,

Kyongtae T. Bae

Publication year - 2010

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.00550110

Subject(s) - cyst , medicine , autosomal dominant polycystic kidney disease , in utero , magnetic resonance imaging , ultrasound , polycystic disease , polycystic kidney disease , nuclear medicine , kidney , radiology , fetus , pregnancy , biology , genetics

In autosomal dominant polycystic kidney disease, cysts derived from tubules are detected at birth by ultrasound (threshold for detection >7.0 mm); thus, fetal cyst growth rates must exceed 2300%/yr. In adults, the combined renal cyst component enlarges at approximately 12%/yr by growth of individual cysts. To explore this discrepancy, the growth rates of individual cysts were determined in adult polycystic kidneys.

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