Effects of Vitamin D2 Supplementation on Vitamin D3 Metabolism in Health and CKD | Zendy

Zona Batacchi | Zendy; Cassianne RobinsonCohen | Zendy; Andrew N. Hoofnagle | Zendy; Tamara Isakova | Zendy; Bryan Kestenbaum | Zendy; Kévin Martin | Zendy; Myles Wolf | Zendy; Ian H. de Boer | Zendy

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Effects of Vitamin D2 Supplementation on Vitamin D3 Metabolism in Health and CKD

Author(s) -

Zona Batacchi,

Cassianne RobinsonCohen,

Andrew N. Hoofnagle,

Tamara Isakova,

Bryan Kestenbaum,

Kévin Martin,

Myles Wolf,

Ian H. de Boer

Publication year - 2017

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.00530117

Subject(s) - vitamin d and neurology , ergocalciferol , medicine , cyp24a1 , endocrinology , vitamin , calcifediol , cholecalciferol , vitamin d deficiency , calcitriol receptor

Vitamin D supplements are prescribed to correct low circulating concentrations of 25-hydroxyvitamin D. In CKD, vitamin D metabolism is complicated by decreased conversion of 25-hydroxyvitamin D to 1,25-dihydroxyvitamin D by CYP27B1 and possibly decreased conversion of 25-hydroxyvitamin D to 24,25-dihydroxyvitamin D by CYP24A1. The aim of this study was to determine the effects of vitamin D 2 supplementation on vitamin D metabolism in health and CKD.

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