Mycophenolic Acid Pharmacokinetics and Relapse in Children with Steroid–Dependent Idiopathic Nephrotic Syndrome | Zendy

Stéphanie Tellier | Zendy; A. Dallocchio | Zendy; Vincent Guigonis | Zendy; F. Saint-Marcoux | Zendy; Brigitte Llanas | Zendy; L. Ichay | Zendy; Isabel Bandı́n | Zendy; A. Godron | Zendy; Denis Morin | Zendy; Karine Brochard | Zendy; Peggy Gandia | Zendy; Stéphane Bouchet | Zendy; Pierre Marquet | Zendy; Stéphane Decramer | Zendy; Jérôme Harambat | Zendy

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Mycophenolic Acid Pharmacokinetics and Relapse in Children with Steroid–Dependent Idiopathic Nephrotic Syndrome

Author(s) -

Stéphanie Tellier,

A. Dallocchio,

Vincent Guigonis,

F. Saint-Marcoux,

Brigitte Llanas,

L. Ichay,

Isabel Bandı́n,

A. Godron,

Denis Morin,

Karine Brochard,

Peggy Gandia,

Stéphane Bouchet,

Pierre Marquet,

Stéphane Decramer,

Jérôme Harambat

Publication year - 2016

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.00320116

Subject(s) - mycophenolic acid , medicine , mycophenolate , nephrotic syndrome , prednisone , therapeutic drug monitoring , area under the curve , gastroenterology , body surface area , pharmacokinetics , pharmacology , transplantation , urology

Therapeutic drug monitoring of mycophenolic acid can improve clinical outcome in organ transplantation and lupus, but data are scarce in idiopathic nephrotic syndrome. The aim of our study was to investigate whether mycophenolic acid pharmacokinetics are associated with disease control in children receiving mycophenolate mofetil for the treatment of steroid-dependent nephrotic syndrome.

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