Randomized Controlled Trial of Individualized Dialysate Cooling for Cardiac Protection in Hemodialysis Patients | Zendy

Aghogho Odudu | Zendy; Mohamed Tarek Eldehni | Zendy; Gerry P McCann | Zendy; Christopher W. McIntyre | Zendy

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Randomized Controlled Trial of Individualized Dialysate Cooling for Cardiac Protection in Hemodialysis Patients

Author(s) -

Aghogho Odudu,

Mohamed Tarek Eldehni,

Gerry P McCann,

Christopher W. McIntyre

Publication year - 2015

Publication title -

clinical journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.755

H-Index - 151

eISSN - 1555-905X

pISSN - 1555-9041

DOI - 10.2215/cjn.00200115

Subject(s) - medicine , randomized controlled trial , hemodialysis , intensive care medicine , cardiology

Cardiovascular disease is the most common cause of death in patients on hemodialysis (HD). HD-associated cardiomyopathy is appreciated to be driven by exposure to recurrent and cumulative ischemic insults resulting from hemodynamic instability of conventionally performed intermittent HD treatment itself. Cooled dialysate reduces HD-induced recurrent ischemic injury, but whether this confers long-term protection of the heart in terms of cardiac structure and function is not known.

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