MATARANINE A AND B: A NEW DIASTOMERIC INDOLE ALKALOID FROM Alstonia scholaris R.Br. OF LOMBOK ISLAND

Alstonia scholaris R. Br., (Apocynaceae) is widely distributed in Indonesia and in Lombok Island, the plant locally known as “lolon nita” has been used to treat malaria. To locate potential bioactive compounds, acid-base extraction was carried out. From the base fraction, two new indole alkaloids with diastomeric structure, named Mataranine A and B, were isolated. The structures of the two alkaloids were elucidated on the basis of UV, NMR and mass spectral data.