ISOLATION OF ACTINOMYCIN D FROM MARINE DERIVED Streptomyces | Zendy

Abdullah Rasyid | Zendy; Kyoko Adachi | Zendy

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ISOLATION OF ACTINOMYCIN D FROM MARINE DERIVED Streptomyces

Author(s) -

Abdullah Rasyid,

Kyoko Adachi

Publication year - 2010

Publication title -

indonesian journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.273

H-Index - 14

eISSN - 2460-1578

pISSN - 1411-9420

DOI - 10.22146/ijc.21683

Subject(s) - strain (injury) , bacteria , chemistry , antibacterial activity , isolation (microbiology) , marine bacteriophage , streptomyces , sponge , bacterial strain , microbiology and biotechnology , seawater , biology , botany , ecology , genetics , anatomy

The bioactive substance producing strain, a marine bacterium A5S-46 was found in the antibacterial screening. This strain was isolated from the artificial sponge set in the coastal seawater at Iriomote islands (Japan). The crude extract from culture broth of the strain A5S-46 was assayed to the antibacterial activity test against the seven kinds of bacterial test strains. The active substance accumulated in the both bacterial cells and culture supernatant. Based on the H NMR and the LC/PDA/MS data, the bioactive substance was identified to be actinomycin D.

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