PHENOLIC COMPOUND FROM THE STEM BARK OF MANGGIS HUTAN (Garcinia bancana Miq.) AND THEIR ANTIOXIDANT ACTIVITY | Zendy

Muharni Muharni | Zendy; Supriyatna Supriyatna | Zendy; Husein H. Bahti | Zendy; Dachriyanus Dachriyanus | Zendy

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PHENOLIC COMPOUND FROM THE STEM BARK OF MANGGIS HUTAN (Garcinia bancana Miq.) AND THEIR ANTIOXIDANT ACTIVITY

Author(s) -

Muharni Muharni,

Supriyatna Supriyatna,

Husein H. Bahti,

Dachriyanus Dachriyanus

Publication year - 2010

Publication title -

indonesian journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.273

H-Index - 14

eISSN - 2460-1578

pISSN - 1411-9420

DOI - 10.22146/ijc.21550

Subject(s) - chemistry , dpph , xanthine oxidase , bark (sound) , antioxidant , garcinia , traditional medicine , ic50 , organic chemistry , biochemistry , enzyme , in vitro , medicine , physics , acoustics

A phenolic compoud, (-)-epicatechin, was isolated from the stem bark of Garcinia bancana. The structure of this compound was determined base on spectroscopic data such as including UV, IR, 1-D, 2-D NMR, and comparison with the reported data. Biological activity of this compound at free radical scavenging activity by 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and inhibitory xanthine oxidase(XO) activity showed that (-)- epicathechin active at two methods with IC50 value 8.1 and 8.6 µg/mL respectively.

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