ANTI DIABETIC FLAVANONE COMPOUND FROM THE LEAVES OF Artocarpus communis | Zendy

Puspa Dewi Lotulung | Zendy; Sofa Fajriah | Zendy; Andini Sundowo | Zendy; Euis Filaila | Zendy

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ANTI DIABETIC FLAVANONE COMPOUND FROM THE LEAVES OF Artocarpus communis

Author(s) -

Puspa Dewi Lotulung,

Sofa Fajriah,

Andini Sundowo,

Euis Filaila

Publication year - 2010

Publication title -

indonesian journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.273

H-Index - 14

eISSN - 2460-1578

pISSN - 1411-9420

DOI - 10.22146/ijc.21524

Subject(s) - flavanone , chemistry , artocarpus , moraceae , ic50 , ethyl acetate , traditional medicine , chromatography , stereochemistry , organic chemistry , biochemistry , botany , flavonoid , in vitro , medicine , biology , antioxidant

The Flavanone compound with anti diabetic activity was isolated from ethyl acetate extract of Artocarpus communis leaves using column chromatography techniques. The structure of the flavanone compound was elucidated on the basic of spectroscopic evidence and comparison to published values. This compound, 8-geranyl4,5,7-trihydroxyflavone, showed strong anti diabetic activity on α-glucosidase inhibition assay with IC50 18.120 μg mL.

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