Open AccessIohexol versus metrizamide for lumbar myelography: double-blind trial
Author(s) -
Trygve O. Gabrielsen,
Stephen S. Gebarśki,
James E. Knake,
J T Latack,
Peter J. Yang,
Julian T. Hoff
Publication year - 1984
Publication title -
american journal of roentgenology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.294
H-Index - 196
eISSN - 1546-3141
pISSN - 0361-803X
DOI - 10.2214/ajr.142.5.1047
Subject(s) - medicine , metrizamide , iohexol , double blind , myelography , lumbar , radiology , nuclear medicine , renal function , spinal cord , pathology , alternative medicine , psychiatry , placebo
Lumbar myelography was performed in 50 patients; 25 received iohexol (an investigational aqueous contrast agent) and 25 received metrizamide. The two media produced radiographs of equal quality. However, iohexol is stable in solution, while metrizamide is not. Further, markedly less morbidity resulted from iohexol. These features indicate that iohexol may be superior to metrizamide as a contrast agent for lumbar myelography.