Open AccessCT of septo-optic dysplasia
Author(s) -
C Manelfe,
P Rochiccioli
Publication year - 1979
Publication title -
american journal of roentgenology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.294
H-Index - 196
eISSN - 1546-3141
pISSN - 0361-803X
DOI - 10.2214/ajr.133.6.1157
Subject(s) - septum pellucidum , medicine , diabetes insipidus , short stature , dysplasia , pituitary stalk , agenesis , hypoplasia , optic nerve hypoplasia , growth hormone deficiency , optic disc , optic chiasma , pneumoencephalography , empty sella syndrome , optic nerve , anatomy , ophthalmology , radiology , glaucoma , pathology , growth hormone , pituitary gland , hormone , surgery
Two girls, aged 7 1/2 and 12 years, clinically suspect for septo-optic dysplasia, were investigated by computed tomography (CT). The clinical picture in both cases associated blindness with hypoplasia of both optic discs, and short stature with growth hormone deficiency. Diabetes insipidus was also present in one case. CT demonstrated agenesis of the septum pellucidum and thin optic nerves. In the case with diabetes insipidus the pituitary stalk was enlarged. It is shown that CT accurately delinerates the altered anatomy of septo-optic dysplasia. CT is recommended rather than pneumoencephalography as the definitive neuroradiologic investigation of these patients.