Initial comparative response to peak pions and x-rays of normal skin and underlying tissue surrounding superficial metastatic nodules | Zendy

M.M. Kligerman | Zendy; Gary West | Zendy; JF Dicello | Zendy; CJ Sternhagen | Zendy; JE Barnes | Zendy; R K LOEFFLER | Zendy; Frank Dobrowolski | Zendy; JN Bradbury | Zendy; T.J.D. Lane | Zendy; DF Petersen | Zendy; Knapp Ea | Zendy

Open Access

Initial comparative response to peak pions and x-rays of normal skin and underlying tissue surrounding superficial metastatic nodules

Author(s) -

M.M. Kligerman,

Gary West,

JF Dicello,

CJ Sternhagen,

JE Barnes,

R K LOEFFLER,

Frank Dobrowolski,

JN Bradbury,

T.J.D. Lane,

DF Petersen,

Knapp Ea

Publication year - 1976

Publication title -

american journal of roentgenology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.294

H-Index - 196

eISSN - 1546-3141

pISSN - 0361-803X

DOI - 10.2214/ajr.126.2.261

Subject(s) - medicine , nodule (geology) , skin reaction , relative biological effectiveness , melanoma , nuclear medicine , pathology , irradiation , dermatology , cancer research , physics , paleontology , nuclear physics , biology

Given the limitations of available material and methods for measuring skin response, the relative biological effectivenss (RBE) for the development and healing of skin reaction to pions in this experiment is 1.43. This is based on data obtained from a patient with malignant melanoma, in whom multiple skin nodules and the surrounding normal skin were randomized into three dose levels for pions and x-rays. The RBE for skin reaction was obtained while the skin tumor nodules appeared to regress at least as rapidly with pion therapy as with x-rays. Without benefit of adequate observation of time required for nodule regrowth, any estimate of tumor RBE is speculative.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research