Unique MRI Findings as an Early Predictor of Osteonecrosis in Pediatric Acute Lymphoblastic Leukemia
Author(s) -
Rakhee Kisan Sansgiri,
Michael D. Neel,
Manuel Soto-Fourier,
Sue C. Kaste
Publication year - 2012
Publication title -
american journal of roentgenology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.294
H-Index - 196
eISSN - 1546-3141
pISSN - 0361-803X
DOI - 10.2214/ajr.11.7367
Subject(s) - medicine , magnetic resonance imaging , complication , surgery , radiology , pelvis
Osteonecrosis is a potential complication of glucocorticoid chemotherapy in children surviving leukemia. Early diagnosis may allow effective interventions to minimize or ameliorate joint deterioration and obviate surgical intervention. We investigated the significance of MRI signal changes that precede the currently recognized "double-line" changes, which are considered pathognomic of osteonecrosis.
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