GERMLINE-GOVERNED RECOGNITION OF A CANCER EPITOPE BY AN IMMUNODOMINANT HUMAN T-CELL RECEPTOR

GERMLINE-GOVERNED RECOGNITION OF A CANCER EPITOPE BY AN IMMUNODOMINANT HUMAN T-CELL RECEPTOR David K Cole, Fang Yuan, Pierre J Rizkallah, John J Miles, Emma Gostick, David A Price, George F Gao, Bent K Jakobsen and Andrew K Sewell These authors contributed equally to this work. Department of Medical Biochemistry & Immunology, Henry Wellcome Building, Cardiff University School of Medicine, Heath Park, Cardiff, CF14 4XN, UK; Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford University, Oxford, OX3 9DU, UK; CLIK, STFC Daresbury Laboratory, Warrington, Cheshire, WA4 4AD, UK; Cellular Immunology Laboratory, Queensland Institute of Medical Research, University of Queensland, Brisbane 4029, Australia; Institute of Microbiology, Chinese Academy of Sciences, Beijing, PR China; Immunocore Limited, 57C Milton Park, Abingdon, Oxon, OX14 4RX, UK. Running head: Innate-like recognition by a human T-cell receptor Address correspondence to: Professor Andrew Sewell. E-mail: sewellak@cardiff.ac.uk. Phone: +44(0)29 206 87055. Fax: +44(0)29 206 87007.