Evaluation of Hepatoprotective Effect of Acantholimon Gilliati Eerial Part Methanolic Extract | Zendy

Rouhollah  Gazor | Zendy; Mehrdad  Asgari | Zendy; Ardalan  Pasdaran | Zendy; Fahimeh  Mohammadghasemi | Zendy; Ebrahim  Nasiri | Zendy; Zahra  Atrkar Roushan | Zendy

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Evaluation of Hepatoprotective Effect of Acantholimon Gilliati Eerial Part Methanolic Extract

Author(s) -

Rouhollah Gazor,

Mehrdad Asgari,

Ardalan Pasdaran,

Fahimeh Mohammadghasemi,

Ebrahim Nasiri,

Zahra Atrkar Roushan

Publication year - 2017

Publication title -

iranian journal of pharmaceutical research : ijpr

Language(s) - English

DOI - 10.22037/ijpr.2017.1994

The aerial parts of Acantholimon gilliati was extracted by n-hexane, dichloromethane and methanol. Methanolic extract tested for hepatoprotective effects on formaldehyde liver injury in mice. The maximum effect that the methanolic extract showed protective effect on this experiment against formaldehyde observed in 5 and 10 mg. Also other concentrations of this extract showed positive effect compared to toxicant on morphology and biochemical factors of the liver. Results showed that the methanolic extract of the A. gilliati has a protective include functional and enzymatic stablingeffect on liver.

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