Study of regulatory promoter polymorphism (-248 G>A) of Bax gene in patients with gastric cancer in the northern provinces of Iran | Zendy

Seyedeh Habibeh Mirmajidi | Zendy; Mojtaba  Najafi | Zendy; Seyedeh Tahereh Mirmajidi | Zendy; Nafiseh  Nasri Nasrabadi | Zendy

Open Access

Study of regulatory promoter polymorphism (-248 G>A) of Bax gene in patients with gastric cancer in the northern provinces of Iran

Author(s) -

Seyedeh Habibeh Mirmajidi,

Mojtaba Najafi,

Seyedeh Tahereh Mirmajidi,

Nafiseh Nasri Nasrabadi

Publication year - 2016

Publication title -

gastroenterology and hepatology from bed to bench

Language(s) - English

DOI - 10.22037/ghfbb.v1i9.802

Aim: The aim of this study is to evaluate the polymorphism in Bax gene and its association with some clinical pathology traits in gastric cancer. Background: Gastric cancer is considered as the fourth most common cancer in the north and northwest of Iran. Bcl2 family has a key role in regulation of apoptosis, and any changes in the expression of Bcl2 lead to cancer. Patients and methods: Blood samples were collected from 100 cases and 89 controls in the northern provinces of Iran to evaluate promoter polymorphism (-248G

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