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Stress to the Rescue: Is Hormesis a ‘Cure’ for Aging?
Author(s) -
Arnold Kahn,
Anders Olsen
Publication year - 2009
Publication title -
dose-response
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.502
H-Index - 36
ISSN - 1559-3258
DOI - 10.2203/dose-response.09-031.olsen
Subject(s) - hormesis , longevity , biology , organism , life expectancy , toxicology , medicine , environmental health , oxidative stress , genetics , population , biochemistry
Despite the fact that the phenomenon of hormesis has been known for many years it is still very much an area of controversy just how useful hormetic treatments are in preventing age-related human diseases and increasing life expectancy. Since there are no data in humans demonstrating hormesis as an effective anti-ageing strategy we turn to a simple model organism for insight. In this review we explore what can be predicted about the usefulness of hormetic treatments in humans based upon studies conducted in the soil nematode Caenorhabditis elegans.

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