Actividad de acetilcolinesterasa y niveles totales de antioxidantes en perros con tumores de mama antes y después de la extirpación quirúrgica
Author(s) -
Joice Lara Maia Faria,
R Rossi,
Aleksandro S. Da Silva,
Nathieli B. Bottari,
Débora Cristina Olsson,
Jéssica L Dalberto,
Ricardo E. Mendes,
Felipe Augusto Ruiz Sueiro,
Wanderson Adriano Biscola Pereira,
Eduardo Negri Mueller,
Maria RC Shetinger,
Naiara dos Santos Guarda,
Rafael Noal Moresco,
Matheus D. Baldissera,
Gustavo Machado
Publication year - 2018
Publication title -
revista mvz córdoba
Language(s) - Spanish
Resource type - Journals
SCImago Journal Rank - 0.202
H-Index - 11
eISSN - 1909-0544
pISSN - 0122-0268
DOI - 10.21897/rmvz.1369
Subject(s) - medicine , gynecology
espanolObjetivo. Evaluar la actividad de la AChE en sangre total y los niveles de FRAP en muestras de perros con tumores mamarios antes y despues de la cirugia, asi como la relacion entre estas variables con marcadores inmunohistoquimicos de tumores (E-caderina, ki-67 , COX - 2). Materiales y metodos. En este estudio, 13 perros con tumores mamarios se dividieron en dos grupos (A y B). El grupo A estaba formado por perros con tumores menores de 3 cm de diametro y el grupo B estaba formado por perros con tumor de 3 cm de diametro o mas. La actividad de AChE y los niveles de FRAP se evaluaron antes y despues de la cirugia y la inmunohistoquimica se realizo en los tumores. Resultados. La actividad de la AChE aumento significativamente (p0.05). Los niveles de FRAP antes de la cirugia fueron significativamente mas bajos (p EnglishObjective. The aim of this study was to evaluate AChE activity in total blood and the FRAP levels in samples from dogs with mammary tumors before and after surgery, as well as the relationship between these variables with immunohistochemical markers of tumor (E-caderina, ki-67, COX-2). Materials and methods. In this study, 13 dogs with mammary tumors were divided into two groups (A and B). The group A was formed by dogs with tumors smaller than 3 cm of diameter, and the group B was formed by dogs with tumor of 3 cm of diameter or larger. The AChE activity and FRAP levels were evaluated before and after surgery and the immunohistochemistry were performed at the tumors. Results. The AChE activity was significantly increased (p0.05). FRAP levels before surgery were significantly lower (p
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