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Some new 3,5-diaryl- N -hydroxy-tetrahydro-1,4-thiazine-1,1-dioxides (6a-i) have been synthesized by reacting thiazine (4) with dimethyldioxirane (5) and tested for their antibacterial and acute toxicity studies. The synthesized compounds were characterized by elemental analysis, IR and NMR spectral data.

Synthesis and biological activities of some 3,5-diaryl-N-hydroxy-tetrahydro-1,4-thiazine-1,1-dioxides