Open AccessSynthesis and biological activities of some 3,5-diaryl-N-hydroxy-tetrahydro-1,4-thiazine-1,1-dioxides
Author(s) -
A. Thangamani
Publication year - 2016
Publication title -
journal of applied and advanced research
Language(s) - English
Resource type - Journals
ISSN - 2519-9412
DOI - 10.21839/jaar.2016.v1i4.36
Subject(s) - thiazine , dimethyldioxirane , chemistry , elemental analysis , carbon 13 nmr , proton nmr , combinatorial chemistry , stereochemistry , organic chemistry
Some new 3,5-diaryl- N -hydroxy-tetrahydro-1,4-thiazine-1,1-dioxides (6a-i) have been synthesized by reacting thiazine (4) with dimethyldioxirane (5) and tested for their antibacterial and acute toxicity studies. The synthesized compounds were characterized by elemental analysis, IR and NMR spectral data.
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