Clinic and immunohistochemical differentiation via cytokeratines of a renal adenocarcinoma in an eight-year-old Hanoverian gelding

Renal adenocarcinoma in horses are challenging to diagnose at an early stage. As horses with renal adenocarcinoma mainly show unspecific symptoms including ongoing weight loss and intermittent fever of unknown origin, neoplasms should be added to the list of differential diagnoses during evaluation of those patients. Via immunohistochemical staining of a biopsy/necropsy specimen of a neoplasia it is possible to track the tumors origin. Using immunohistochemical staining to proof the tumor’s origin might be beneficial for making the decision to treat a horse surgically or euthanize it.