Open AccessEen degeneratieve gewrichtsaandoening behandeld met autologe equine mesenchymale stamcellen uit het perifeer bloed
Author(s) -
Jan H. Spaas,
Maarten Oosterlinck,
Sarah Broeckx,
Michèle Dumoulin,
Jimmy Saunders,
Ann Van Soom,
Frederik Pille,
Gerlinde Van de Walle
Publication year - 2012
Publication title -
vlaams dierengeneeskundig tijdschrift
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.176
H-Index - 18
ISSN - 0303-9021
DOI - 10.21825/vdt.v81i1.18372
Subject(s) - gynecology , medicine
A 5-year-old German Warmblood stallion with chronic lameness, attributable to degenerative joint disease (DJD) of the pastern joint unresponsive to medical treatments, was treated with autologous mesenchymal stem cells (MSC). These MSC were isolated from the peripheral blood (PB) of the patient and injected into the pastern joint, at a concentration of 2.5x106 cells, twice with an 8-week interval. The positive response to this stem cell treatment was documented by visual gait evaluation as well as objective pressure plate analyses. This paper is the first to describe the use of autologous PB-derived MSC to treat a horse suffering from chronic DJD. The favorable outcome of this single case may stimulate further research on the use of equine peripheral blood as a source of autologous MSC in equine regenerative medicine.