PFAPA Syndrome (Periodic fever, Aphthous stomatitis, Pharyngitis and Adenitis)

PFAPA syndrome is a febril disease with unknown etiology which is characterized by reccurrent aphthous stomatitis, pharyngitis and servical adenitis. It has a benign clinical course and frequently seen in male patients under five-year-old. Although the clinical findings of PFAPA is specific, its diagnosis is often diffucult due to non-specific laboratory findings. In this report, we discuss two patients diagnosed with PFAPA syndrome. PFAPA sendromu; tekrarlayici, aftoz stomatit, farenjit ve servikal lenfadenopati ataklarinin eslik ettigi etyolojisi henuz tam olarak bilinmeyen atesli bir hastaliktir.  Benign karakterde olup bes yasindan kucuklerde ve erkek cinsiyette daha sik gorulur. Uzun donemde sekel gelismez. Hastaligin klinik tablosu spesifik olmasina ragmen laboratuvar bulgularinin non-spesifik olmasi nedeniyle tanisi guctur. Bu olgu sunumunda klinige basvuran ve PFAPA tanisi konulan iki hasta tartisildi.