Structure, Function and Regulation of the Clostridium cellulovorans Cellulosome
Author(s) -
Roy H. Doi
Publication year - 2008
Publication title -
osti oai (u.s. department of energy office of scientific and technical information)
Language(s) - English
Resource type - Reports
DOI - 10.2172/951625
Subject(s) - cellulosome , clostridium thermocellum , function (biology) , clostridium , computational biology , bacillus subtilis , biology , chemistry , cellulase , microbiology and biotechnology , biochemistry , enzyme , bacteria , genetics
Our major goal for this project (2004-2008) was to obtain an understanding ofthe structure, function, and regulation of the Clostridium cellulovorans cellulosomes. Our specific goals were to select genes for cellulosomal and non-cellulosomal enzymes and characterize their products, to study the synergistic action between cellulosomal and non-cellulosomal enzymes, to study the composition of cellulosomes when cells were grown with different carbon sources, continue our studies on the scaffolding protein and examine heterologous expression of cellulosomal genes in Bacillus subtilis. We fulfilled the specific goals of our proposal
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