Field-Portable Immunoassay Instruments and Reagents to Measure Chelators and Mobile Forms of Uranium
Author(s) -
Diane A. Blake
Publication year - 2001
Publication title -
osti oai (u.s. department of energy office of scientific and technical information)
Language(s) - English
Resource type - Reports
DOI - 10.2172/893872
Subject(s) - uranium , immunoassay , reagent , chemistry , monoclonal antibody , chelation , chromatography , measure (data warehouse) , computer science , radiochemistry , antibody , materials science , inorganic chemistry , data mining , biology , metallurgy , immunology
Previous studies from our laboratory have demonstrated the feasibility of immunoassays for identification and quantification of specific metal ions. Our ultimate goal for this project is to (1) isolate and characterize antibodies that recognize the most mobile form of uranium, UO22+; (2) assemble, test, and validate a new field-portable immunosensor based on these antibodies; (3) prepare new monoclonal antibodies to the primary chelators (EDTA and DTPA) found in DOE wastes
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