Open AccessExploratory research into pathogen surface interactions.
Author(s) -
Michael B. Sinclair,
Todd W. Lane,
Howland D. T. Jones,
Roberto Rebeil,
Susan J. Altman,
Julie Kaiser,
Lucas K. McGrath,
Caroline Ann Souza
Publication year - 2006
Language(s) - English
Resource type - Reports
DOI - 10.2172/877739
Subject(s) - legionella , francisella , biofilm , microbiology and biotechnology , biology , francisella tularensis , bacteria , genetics , virulence , gene
In this short-duration project the research team was able to achieve growth of both drinking water biofilms and monospecific biofilms of Legionella pneurnophila. Preliminary comparative proteomic analyses were carried out on planktonic and biofilm-associated Legionella. After delay for completion of permitting and review by the director of the National Institutes for Allergy and Infectious Disease, the Utah 112 strain of Francisella novicida was obtained and preliminary culture and comparative proteomic analyses were carried out. Comprehensive literature searches and data mining were carried out on all research topics