LATERAL GENE TRANSFER AND THE HISTORY OF BACTERIAL GENOMES | Zendy

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LATERAL GENE TRANSFER AND THE HISTORY OF BACTERIAL GENOMES

Author(s) -

Howard Ochman

Publication year - 2006

Publication title -

osti oai (u.s. department of energy office of scientific and technical information)

Language(s) - English

Resource type - Reports

DOI - 10.2172/876510

Subject(s) - horizontal gene transfer , genome , bacterial genome size , biology , gene , gene transfer , genetics , bacteria , evolutionary biology , computational biology

The aims of this research were to elucidate the role and extent of lateral transfer in the differentiation of bacterial strains and species, and to assess the impact of gene transfer on the evolution of bacterial genomes. The ultimate goal of the project is to examine the dynamics of a core set of protein-coding genes (i.e., those that are distributed universally among Bacteria) by developing conserved primers that would allow their amplification and sequencing in any bacterial taxa. In addition, we adopted a bioinformatic approach to elucidate the extent of lateral gene transfer in sequenced genome

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