Open AccessEnvironmentally-Induced Malignancies: An In Vivo Model to Evaluate the Health Impact of Chemicals in Mixed Waste
Author(s) -
Maria Pallavicini
Publication year - 2001
Language(s) - English
Resource type - Reports
DOI - 10.2172/792424
Subject(s) - hazardous waste , waste management , environmental chemistry , contamination , radioactive waste , organic chemicals , heavy metals , environmental science , chemistry , ecology , engineering , biology
Occupational and environmental exposure to organic ligands, solvents, fuel hydrocarbons, and polychlorinated biphenyls are linked with increased risk of hematologic malignancies. DOE facilities and waste sites in the U.S. are contaminated with mixtures of potentially hazardous chemicals such as metals, organic ligands, solvents, fuel hydrocarbons, polychlorinated biphenyls and radioactive isotopes. A major goal of this project was to establish linkage between chemical/radiation exposure and induction of genomic damage in target populations with the capability to undergo transformation